BDBM13286 4-Hydroxy-3-[3-(S)-(7-methoxynaphthalen-2-ylsulfonylamino)-2-oxopyrrolidin-1-ylmethyl]benzamidine::4-hydroxy-3-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfonamido]-2-oxopyrrolidin-1-yl]methyl}benzene-1-carboximidamide::CHEMBL93854::Sulfonamidopyrrolidinone 20a

SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2cc(ccc2O)C(N)=N)C1=O

InChI Key InChIKey=WYPLWOJSDQFHPG-FQEVSTJZSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13286   

TargetSerine protease 1(Bos taurus (bovine))
Rhone-Poulenc Rorer

LigandPNGBDBM13286(4-Hydroxy-3-[3-(S)-(7-methoxynaphthalen-2-ylsulfon...)
Affinity DataKi:  305nM ΔG°:  -8.79kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM13286(4-Hydroxy-3-[3-(S)-(7-methoxynaphthalen-2-ylsulfon...)
Affinity DataKi:  305nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed